Motif ID: DMAP1_NCOR{1,2}_SMARC.p2

Z-value: 0.375


Transcription factors associated with DMAP1_NCOR{1,2}_SMARC.p2:

Gene SymbolEntrez IDGene Name
DMAP1 55929 DNA methyltransferase 1 associated protein 1
NCOR1 9611 nuclear receptor co-repressor 1
NCOR2 9612 nuclear receptor co-repressor 2
SMARCA1 6594 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SMARCA5 8467 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMARCC2 6601 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMARCA1chrX_-_1286574400.831.1e-02Click!
SMARCC2chr12_-_565832440.733.9e-02Click!
DMAP1chr1_+_446791110.705.1e-02Click!
SMARCA5chr4_+_144434555-0.696.0e-02Click!
NCOR2chr12_-_1250520090.147.5e-01Click!
NCOR1chr17_-_160978820.127.8e-01Click!


Activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2.

activity profile for motif DMAP1_NCOR{1,2}_SMARC.p2


Sorted Z-values histogram for motif DMAP1_NCOR{1,2}_SMARC.p2

Sorted Z-values for motif DMAP1_NCOR{1,2}_SMARC.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DMAP1_NCOR{1,2}_SMARC.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_159175048 0.616 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr5_+_92918924 0.424 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr8_-_12973752 0.318 NM_001164271
DLC1
deleted in liver cancer 1
chr1_-_168698412 0.293 NM_001937
DPT
dermatopontin
chr8_-_108510094 0.252 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr5_-_19988293 0.237 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr6_+_72596699 0.219 RIMS1
regulating synaptic membrane exocytosis 1
chr5_+_71502700 0.211 MAP1B
microtubule-associated protein 1B
chr7_-_92777657 0.211 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr13_+_24144402 0.211 NM_001204459
NM_148957
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr6_+_72596405 0.207 RIMS1
regulating synaptic membrane exocytosis 1
chr5_-_154230157 0.203 C5orf4
chromosome 5 open reading frame 4
chr5_-_154230212 0.194 NM_032385
C5orf4
chromosome 5 open reading frame 4
chr2_-_188419185 0.193 NM_001032281
NM_006287
TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr1_+_221052735 0.188 NM_021958
HLX
H2.0-like homeobox
chr1_+_221052845 0.185 HLX
H2.0-like homeobox
chr16_-_4896197 0.182 GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr6_+_72922513 0.180 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr1_+_221053000 0.179 HLX
H2.0-like homeobox
chr6_+_136172802 0.166 NM_018945
PDE7B
phosphodiesterase 7B
chr20_-_34025955 0.161 NM_000557
GDF5
growth differentiation factor 5
chr1_+_114522029 0.161 NM_020190
OLFML3
olfactomedin-like 3
chr11_-_104916041 0.157 NM_001017534
NM_052889
CARD16

caspase recruitment domain family, member 16

chr17_+_6659356 0.157 XAF1
XIAP associated factor 1
chr2_-_188419049 0.155 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr6_+_31623668 0.146 NM_019101
APOM
apolipoprotein M
chr5_+_140602914 0.144 NM_018934
PCDHB14
protocadherin beta 14
chr12_-_54867372 0.143 NM_144594
GTSF1
gametocyte specific factor 1
chr11_+_63304272 0.141 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr3_-_49851217 0.139 UBA7
ubiquitin-like modifier activating enzyme 7
chr4_-_39640461 0.134 NM_174921
C4orf34
chromosome 4 open reading frame 34
chr5_+_140810181 0.133 PCDHGA12
protocadherin gamma subfamily A, 12
chr2_+_152214105 0.133 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr4_-_159094163 0.132 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr6_+_31623688 0.131 APOM
apolipoprotein M
chr19_-_17516383 0.129 NM_004335
BST2
bone marrow stromal cell antigen 2
chr6_-_138820580 0.129


chr6_+_72596648 0.124 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr2_+_210444154 0.124 MAP2
microtubule-associated protein 2
chr2_-_200325200 0.124 SATB2
SATB homeobox 2
chr11_+_5710926 0.123 TRIM22
tripartite motif containing 22
chr3_+_49449753 0.122 TCTA
T-cell leukemia translocation altered gene
chr14_+_21152735 0.121 ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr3_+_69812961 0.118 NM_006722
MITF
microphthalmia-associated transcription factor
chr5_+_59784004 0.117 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr6_+_132129195 0.116 ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr1_+_79115476 0.116 NM_006417
IFI44
interferon-induced protein 44
chr11_-_64527369 0.115 PYGM
phosphorylase, glycogen, muscle
chr1_+_101185195 0.115 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr4_+_124317884 0.114 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr18_+_72922725 0.114 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr10_+_69869249 0.112 NM_032578
MYPN
myopalladin
chr3_+_49449638 0.111 NM_022171
TCTA
T-cell leukemia translocation altered gene
chr5_-_138775138 0.111 DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr4_+_77953942 0.110 SEPT11
septin 11
chr2_-_37899227 0.110 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr17_-_67138013 0.110 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr20_+_12989616 0.105 NM_018327
SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr10_-_70066594 0.105 PBLD
phenazine biosynthesis-like protein domain containing
chr1_+_948846 0.104 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr10_-_14372807 0.104 NM_018027
FRMD4A
FERM domain containing 4A
chr11_+_65192284 0.102 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr1_-_57431620 0.102 NM_000066
C8B
complement component 8, beta polypeptide
chr3_+_157154579 0.100 NM_002852
PTX3
pentraxin 3, long
chr11_+_5710816 0.100 NM_001199573
NM_006074
TRIM22

tripartite motif containing 22

chr2_-_238322770 0.099 COL6A3
collagen, type VI, alpha 3
chr17_+_6659155 0.098 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr5_+_140810126 0.097 NM_003735
NM_032094
PCDHGA12

protocadherin gamma subfamily A, 12

chr4_+_55095263 0.096 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr11_+_65268313 0.096 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr2_-_211179765 0.095 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr14_-_73493744 0.094 NM_021260
ZFYVE1
zinc finger, FYVE domain containing 1
chr14_+_21156922 0.094 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr3_+_69812620 0.093 NM_001184967
MITF
microphthalmia-associated transcription factor
chrX_+_88002225 0.092 NM_001184771
NM_033048
CPXCR1

CPX chromosome region, candidate 1

chr14_-_24683035 0.091 NM_014169
CHMP4A
charged multivesicular body protein 4A
chr5_+_140753480 0.091 NM_018919
NM_032086
PCDHGA6

protocadherin gamma subfamily A, 6

chr1_+_229440128 0.091 NM_006542
SPHAR
S-phase response (cyclin related)
chrX_+_100333835 0.090 NM_021637
TMEM35
transmembrane protein 35
chrX_-_63005212 0.090 NM_001173479
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr3_-_151987332 0.089 LOC401093
uncharacterized LOC401093
chr5_-_176738831 0.089 MXD3
MAX dimerization protein 3
chr6_+_73076431 0.087 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr5_-_158526698 0.084 NM_024007
EBF1
early B-cell factor 1
chr1_+_84609941 0.083 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_64052164 0.083 NM_004322
NM_032989
BAD

BCL2-associated agonist of cell death

chrX_+_79675945 0.081 NM_152630
FAM46D
family with sequence similarity 46, member D
chrX_-_135863033 0.081 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr11_-_2018568 0.080 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr4_-_186733372 0.080 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr3_+_154798078 0.080 NM_007289
MME
membrane metallo-endopeptidase
chr20_-_57089845 0.080 NM_153360
APCDD1L
adenomatosis polyposis coli down-regulated 1-like
chrX_+_135251795 0.080 NM_001167819
FHL1
four and a half LIM domains 1
chr14_+_74003817 0.080 NM_001037161
ACOT1
acyl-CoA thioesterase 1
chr10_+_91092238 0.079 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr15_-_48937795 0.079 NM_000138
FBN1
fibrillin 1
chr5_-_138775213 0.079 NM_152686
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chrX_+_85517970 0.079 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chr16_+_4430878 0.078 VASN
vasorin
chr11_-_27681195 0.077 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr3_-_100712248 0.077 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr3_+_119316694 0.076 NM_001206960
NM_001206961
NM_015900
PLA1A


phospholipase A1 member A


chr3_+_45927995 0.076 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chrX_+_80457559 0.076 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr5_+_133842276 0.076


chrX_-_18372777 0.075 NM_006089
SCML2
sex comb on midleg-like 2 (Drosophila)
chr1_-_163172624 0.074 NM_001195303
RGS5
regulator of G-protein signaling 5
chr12_-_10324675 0.074 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr1_-_151319717 0.073 NM_000449
NM_001025603
RFX5

regulatory factor X, 5 (influences HLA class II expression)

chr2_-_214015053 0.072 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr19_+_17516502 0.072 LOC100507535
uncharacterized LOC100507535
chr4_-_159092509 0.071 FAM198B
family with sequence similarity 198, member B
chr13_+_49550949 0.071 FNDC3A
fibronectin type III domain containing 3A
chr2_-_68547018 0.071 NM_001111101
NM_015463
CNRIP1

cannabinoid receptor interacting protein 1

chr3_-_45267068 0.070 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr4_-_57547845 0.070 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr18_-_3011944 0.070 NM_014646
LPIN2
lipin 2
chr8_-_93029864 0.070 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_167232464 0.069 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr10_+_91152321 0.069 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr1_-_151319674 0.068 RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr16_+_15528324 0.068 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr8_-_60031545 0.068 NM_014729
TOX
thymocyte selection-associated high mobility group box
chr17_-_8702438 0.068 NM_152599
MFSD6L
major facilitator superfamily domain containing 6-like
chr19_+_10197023 0.067 C19orf66
chromosome 19 open reading frame 66
chr3_+_159557745 0.067 SCHIP1
schwannomin interacting protein 1
chr2_+_210444364 0.067 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr19_+_10196972 0.066 C19orf66
chromosome 19 open reading frame 66
chr17_-_29641068 0.066 EVI2B
ecotropic viral integration site 2B
chr15_+_97326629 0.065 NM_173499
SPATA8
spermatogenesis associated 8
chr16_+_8814567 0.064 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr11_-_64052123 0.064 BAD
BCL2-associated agonist of cell death
chr3_+_187086167 0.063 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr6_+_25962978 0.063 NM_006355
TRIM38
tripartite motif containing 38
chr6_-_167571315 0.062 NM_005299
GPR31
G protein-coupled receptor 31
chr3_-_49851356 0.062 NM_003335
UBA7
ubiquitin-like modifier activating enzyme 7
chr19_-_10679328 0.062 CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr1_+_162602308 0.061 DDR2
discoidin domain receptor tyrosine kinase 2
chr4_-_186732208 0.061 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr4_+_74347461 0.061 NM_001133
AFM
afamin
chr4_-_159093717 0.060 NM_016613
FAM198B
family with sequence similarity 198, member B
chr9_-_73029539 0.060 NM_001206
KLF9
Kruppel-like factor 9
chr14_+_76618272 0.060 C14orf118
chromosome 14 open reading frame 118
chr5_-_169724614 0.059 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_138775189 0.059 DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr6_+_25963398 0.059 TRIM38
tripartite motif containing 38
chr1_-_113161724 0.059 NM_017744
NM_138727
NM_138728
NM_138729
ST7L



suppression of tumorigenicity 7 like



chr11_-_2019007 0.059 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chrX_+_9431314 0.058 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr3_+_29322802 0.058 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr1_+_202431870 0.058 NM_032103
NM_032104
PPP1R12B

protein phosphatase 1, regulatory subunit 12B

chr18_-_25756946 0.058 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr1_+_162602198 0.057 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr10_-_74283693 0.057 NM_001195519
MICU1
mitochondrial calcium uptake 1
chr16_+_55600583 0.057 NM_032330
CAPNS2
calpain, small subunit 2
chr19_-_44384240 0.056 NM_001033719
ZNF404
zinc finger protein 404
chr3_-_50374875 0.056 NM_170713
RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr8_+_17396285 0.056 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr3_-_122283423 0.056 NM_001146103
NM_031458
PARP9

poly (ADP-ribose) polymerase family, member 9

chr6_+_44126547 0.056 NM_007058
CAPN11
calpain 11
chr20_-_39946119 0.056 ZHX3
zinc fingers and homeoboxes 3
chr3_+_49059046 0.056 NM_199069
NM_199070
NDUFAF3

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3

chrX_-_106960268 0.055 NM_004089
TSC22D3
TSC22 domain family, member 3
chr3_-_169587598 0.054 NM_024727
LRRC31
leucine rich repeat containing 31
chr12_-_7245006 0.054 NM_001733
C1R
complement component 1, r subcomponent
chr1_-_46598250 0.054 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr3_+_159557649 0.054 NM_001197109
SCHIP1
schwannomin interacting protein 1
chrX_+_110366304 0.054 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr1_+_244998592 0.054 NM_198076
FAM36A
family with sequence similarity 36, member A
chr13_+_49550911 0.053 FNDC3A
fibronectin type III domain containing 3A
chr2_-_230579198 0.053 NM_139072
DNER
delta/notch-like EGF repeat containing
chr19_-_18508407 0.053 NM_145256
LRRC25
leucine rich repeat containing 25
chr1_-_113162215 0.052 ST7L
suppression of tumorigenicity 7 like
chr11_-_102595623 0.052 NM_002424
MMP8
matrix metallopeptidase 8 (neutrophil collagenase)
chr1_-_173886401 0.052 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr9_-_21202201 0.051 NM_021057
IFNA7
interferon, alpha 7
chr6_+_31913708 0.051 NM_001710
CFB
complement factor B
chr13_+_49822046 0.051 NM_001193478
NM_030911
CDADC1

cytidine and dCMP deaminase domain containing 1

chr10_-_44063906 0.051 NM_005674
ZNF239
zinc finger protein 239
chr6_+_132129154 0.051 NM_006208
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr7_+_100728719 0.051 NM_030961
TRIM56
tripartite motif containing 56
chr17_-_67311773 0.051 NM_018672
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr20_-_35488275 0.050 NM_199181
KIAA0889
KIAA0889
chr4_+_41614725 0.050 LIMCH1
LIM and calponin homology domains 1
chrX_-_135863104 0.050 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_-_46357949 0.050


chr6_+_108881010 0.050 NM_201559
FOXO3
forkhead box O3
chr6_+_31913763 0.050 CFB
complement factor B
chr17_-_39183453 0.049 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr1_+_145096391 0.049 NM_004892
SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chr6_-_48078909 0.049 C6orf138
chromosome 6 open reading frame 138
chr8_-_87520849 0.049 FAM82B
family with sequence similarity 82, member B
chr1_+_51434375 0.049 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr20_-_47894591 0.049 NM_021035
ZNFX1
zinc finger, NFX1-type containing 1
chr3_+_154797910 0.049 NM_007288
MME
membrane metallo-endopeptidase
chr11_-_2170792 0.048 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr3_+_138066489 0.048 NM_001252091
NM_012219
MRAS

muscle RAS oncogene homolog

chr17_-_46688279 0.048 HOXB7
homeobox B7
chr20_+_34995443 0.047 NM_014902
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr3_-_15839674 0.047 NM_001195098
ANKRD28
ankyrin repeat domain 28

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 3.50e-04 GO:0060255 regulation of macromolecule metabolic process
1.33 3.94e-04 GO:0080090 regulation of primary metabolic process
1.31 1.31e-03 GO:0031323 regulation of cellular metabolic process
4.08 2.39e-03 GO:0034340 response to type I interferon
1.28 3.34e-03 GO:0019222 regulation of metabolic process
1.75 4.43e-03 GO:0006955 immune response
1.38 5.12e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.36 8.19e-03 GO:0010556 regulation of macromolecule biosynthetic process
3.89 9.99e-03 GO:0060337 type I interferon-mediated signaling pathway
3.89 9.99e-03 GO:0071357 cellular response to type I interferon
1.34 1.27e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.37 1.28e-02 GO:0048519 negative regulation of biological process
1.33 1.70e-02 GO:0009889 regulation of biosynthetic process
1.34 1.77e-02 GO:0031326 regulation of cellular biosynthetic process
1.37 1.87e-02 GO:0051252 regulation of RNA metabolic process
1.17 2.11e-02 GO:0050794 regulation of cellular process
1.37 2.36e-02 GO:0006355 regulation of transcription, DNA-dependent
1.33 2.60e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.16 3.00e-02 GO:0050789 regulation of biological process
1.33 3.56e-02 GO:0010468 regulation of gene expression
1.15 3.58e-02 GO:0065007 biological regulation
1.37 3.86e-02 GO:0048523 negative regulation of cellular process
1.34 4.62e-02 GO:0006950 response to stress

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.68 1.69e-04 GO:0001071 nucleic acid binding transcription factor activity
1.68 1.69e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
2.88 5.20e-04 GO:0003714 transcription corepressor activity
1.73 3.66e-03 GO:0043565 sequence-specific DNA binding
10.04 2.43e-02 GO:0005132 interferon-alpha/beta receptor binding
1.08 2.88e-02 GO:0005488 binding
1.14 4.58e-02 GO:0005515 protein binding